PH9305 | Trolox 奎诺二甲基丙烯酸酯 水溶性维生素E CAS: 53188-07-1

英文名称：Trolox；3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1-benzopyran-2-carboxylicaci;troloxc;6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLICACID;(+/-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMANE-2-CARBOXYLICACID;TROLOX;TROLOX(R);TROLOXTMC
其他名称：2,5,7,8-四甲基-6-羟基苯并二氢吡喃-2-甲酸；特罗洛克斯杂质；奎诺二甲基丙烯酸；水溶性维生素E
CAS号：53188-07-1
C14H18O4=250.29
级别：BR
紫外光谱：合格
含量：≥98.0%
用途：本品仅供科研，不得用于其它用途。
保存：常温运输，2～8℃保存，有效期2年。


Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage.


Trolox has shown to protect mammalian cells from oxidative damage. Trolox is effective in preventing myocyte necrosis in cell culture studies and in a canine model of two hours of left anterior descending coronary artery (LAD) occlusion followed by four hours of reperfusion.
Trolox could prevent oxidative stress-induced apoptosis in thymocytes. Pre- or posttreatment of cells with Trolox reduced H2O2-induced DNA fragmentation to control levels and below. 


Trolox is a hydrophilic analogue of alpha-tocopherol and reported to scavenge peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes. Trolox prolongs substantially the survival of human ventricular myocytes and hepatocyte against oxyradicals generated with xanthine oxidase plus hypoxanthine, and prevented lysis of red cells exposed to an azo-initiator.